Humoral control of airway tone.
نویسندگان
چکیده
منابع مشابه
The gain of smooth muscle's contractile capacity induced by tone on in vivo airway responsiveness in mice.
Airway hyperresponsiveness to a spasmogenic challenge such as methacholine, and an increased baseline tone measured by the reversibility of airway obstruction with a bronchodilator, are two common features of asthma. However, whether the increased tone influences the degree of airway responsiveness to a spasmogen is unclear. Herein, we hypothesized that increased tone augments airway responsive...
متن کاملEffect of airway smooth muscle tone on airway distensibility measured by the forced oscillation technique in adults with asthma.
Airway distensibility appears to be unaffected by airway smooth muscle (ASM) tone, despite the influence of ASM tone on the airway diameter-pressure relationship. This discrepancy may be because the greatest effect of ASM tone on airway diameter-pressure behavior occurs at low transpulmonary pressures, i.e., low lung volumes, which has not been investigated. Our study aimed to determine the con...
متن کاملMeasurement of intraindividual airway tone heterogeneity and its importance in asthma
While airways have some degree of baseline tone, the level and variability of this tone is not known. It is also unclear whether there is a difference in airway tone or in the variability of airway tone between asthmatic and healthy individuals. This study examined airway tone and intraindividual airway tone heterogeneity (variance of airway tone) in vivo in 19 individuals with asthma compared ...
متن کاملInvited Review HIGHLIGHTED TOPIC Reflexes from the Lungs and Airways Reflex regulation of airway smooth muscle tone
Canning, Brendan J. Reflex regulation of airway smooth muscle tone. J Appl Physiol 101: 971–985, 2006. doi:10.1152/japplphysiol.00313.2006.—Autonomic nerves in most mammalian species mediate both contractions and relaxations of airway smooth muscle. Cholinergic-parasympathetic nerves mediate contractions, whereas adrenergic-sympathetic and/or noncholinergic parasympathetic nerves mediate relaxa...
متن کاملSensitivity of the Large Blood Vessels of the Rabbit to i-Epinephrine and i-Norepinephrine
THE LARGE arteries and veins do more than conduct blood to and from the heart. They act as central, elastic, volume reservoirs. Their walls contain vascular smooth muscle under nervous and humoral control and also many of the receptors that maintain homeostasis. The tone of this smooth muscle varies in response to pharmacological and humoral stimuli and, consequently, changes the activity of th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Thorax
دوره 51 5 شماره
صفحات -
تاریخ انتشار 1996